Santiago Giraldo - 2.5 games v Gastao Elias: There is plenty of rain around Brazil at the moment which had affected the tournament in Rio last week and is set to disrupt the Sao Paulo tournament too. Wednesday was effectively written off which means we have a full Second Round schedule to get through on Thursday, although I wouldn't be holding my breath that they are able to get through the whole day without more rain.
That does make it difficult for the players having to warm up and warm down during matches while it isn't any easier for those scheduled for later in the day as they have to wait around. That might be the case for Santiago Giraldo and Gastao Elias in their Second Round match which is expected to be closer than I would have had it myself.
They did have a tight match in Rio de Janeiro last week, but I think Giraldo was looking the stronger player in that match and I expect the Colombian to frank that win here. He played very well in the First Round and it has to be remembered that Elias usually plays at a lower level with more Challengers in his future than there will be these main draws.
Elias has played well over the last couple of weeks to show he might be capable of bridging the gap, but Giraldo is the better player in this one. It might be a similar scoreline to last time, but I have a feeling Giraldo will find a break more in each set and I like him coming through 64, 64 to move into the Quarter Final.
Pablo Cuevas - 4.5 games v Facundo Bagnis: Winning the title in Rio de Janeiro, the biggest of his career, should be the kind of confidence builder that can see Pablo Cuevas perhaps achieve the goals he has set for himself. There was plenty of belief in the way he played last week and I think he might be glad of the rain which will mean his first match here is delayed until this moment.
It might be a little longer that Cuevas has to wait to get his event underway, but he should be happy with the match up against Facundo Bagnis who will give him a decent rhythm from the back of the court.
They met last meet and Cuevas won very easily, but that is unlikely to be the case again. Bagnis has put together three solid wins this week to get into the Second Round and I think he will have learnt something from the lesson that was handed out to him by Cuevas.
In saying that, I do think Cuevas is the far stronger player and he loves the clay courts in South America. With the extra time to recover I think he will be ready for this event in Sao Paulo and while it will be closer than last week, I still believe Cuevas is good enough to win this one 63, 64 and book his place in the Quarter Final.
Bernard Tomic - 3.5 games v Illya Marchenko: There were some sloppy moments in the Bernard Tomic win over Adrian Mannarino, but the Australian knuckled down at key moments to ensure he moved into the Quarter Final in straight sets. He will need to continue his focus if he is going to see off Illya Marchenko who is a player that can produce some fine tennis on his day.
Marchenko has already reached one Semi Final on the main Tour this season so I don't imagine nerves are going to bother him that much. However he has also had some silly losses since that Semi Final in Doha and it can be hard to figure out what kind of form he will bring to the table.
It will need to be his best to see off Tomic who has enjoyed his time on the South and Central American hard courts in his career. He regularly performs well in Bogota in Colombia later in the season and Tomic has looked a little more focused this week even through some of the inconsistent moments.
This is certainly a big event for Tomic who has made his top ten ambitions very clear to the media and picking up the Ranking points from a deep run in an ATP 500 event is certainly the way to go. That should keep him focused in this one and I think Tomic will find his way to break down Marchenko in a 64, 64 win.
Dominic Thiem + 2.5 games v Grigor Dimitrov: When this match was set and before the prices were released, I really thought it was going to be a pick 'em Quarter Final between Grigor Dimitrov and Dominic Thiem. It is going to be a close match to call so I would not have played it, but I can't stand by and see Thiem as a fairly big underdog being given this many games on the handicap.
The bigger 'name' is definitely Dimitrov for the casual fans, but I don't think he has been in the kind of form that his straight set wins over Denis Kudla and Donald Young may suggest. Dimitrov had to dig deep in both of those matches and now he is facing a much better player in Thiem who has the confidence of a title win and a Semi Final run behind him.
Perhaps the clay courts are more to Thiem's liking at this moment in his career, but he is more than capable of producing on the hard courts. He has some power behind him and Thiem won't be intimidated by facing Dimitrov but instead may look at this as a chance to show there is a 'new kid on the block'.
I might be completely wrong and Dimitrov dominates this match from start to finish, but I think he is not serving as well as the scores might suggest. He will give Thiem chances and I think the upset has every chance of being achieved in this one.
However I will take the security of the games and look for a very competitive showing from Thiem in this one.
Sam Querrey - 1.5 games v Taylor Fritz: This looks a fascinating match between the last generation of American players and the next.
You can't help but be impressed with Taylor Fritz and the way he has performed on the main Tour after a strong Junior season in 2015. He is set to break into the top 100 in the World Rankings on Monday and Fritz has already reached a Final in Memphis to back up a Challenger win earlier in the season.
Fritz has won some solid matches this week against the likes of Jeremy Chardy and Victor Estrella Burgos, but I do think the level steps up when facing the Delray Beach Champion Sam Querrey. I have to say I wasn't sure Querrey was going to do anything but slip down the World Rankings, but he looks revitalised and the serve continues to be a huge weapon for him.
If he is serving well it will build plenty of scoreboard pressure on Fritz and I think the youngster might just struggle to cope in this one. I do think he could have big things in his future, but I also believe Querrey is in hot form and can come through this one 76, 64.
Santiago Giraldo - 2.5 Games @ 1.75 Bet Victor (2 Units)
Pablo Cuevas - 4.5 Games @ 1.91 William Hill (2 Units)
Bernard Tomic - 3.5 Games @ 1.80 Ladbrokes (2 Units)
Dominic Thiem + 2.5 Games @ 1.91 Bet Fred (2 Units)
Sam Querrey - 1.5 Games @ 2.10 William Hill (2 Units)